What is the role of neoadjuvant chemotherapy in advanced ovarian cancer?

Patients with large tumours and stage III/IV ovarian cancer who are poor candidates for surgery due to high risk conditions or disease factors can consider neoadjuvant chemotherapy, whereby chemotherapy is given before the main treatment (usually surgery) is given. Patients being evaluated for neoadjuvant chemotherapy should be seen by a trained gynaecologic oncologist before being considered a poor candidate for surgery.

They can also consider surgical removal of tumour before or after chemotherapy. Published data demonstrates that primary assessments and surgical removal of tumours by a gynaecologic oncologist improves survival.