What are recommendations for second-line palliative chemotherapy for soft tissue sarcoma?

Treatment is dependent on the type of cancer but in general options include:

1. Ifosfamide, an anticancer agent that makes DNA stick together so cancer cells cannot grow.

2. Gemcitabine and docetaxel. Gemcitabine is a drug that inhibits cancer cell growth and promotes cancer cell death. Docetaxel is an anti-cancer drug that inhibits cancer cell division.

3. Gemcitabine and dacarbazine. Dacarbazine is a drug that kills cancer cells by destroying their DNA.

4. Gemcitabine.

5. Pazopanib, a drug that inhibits the growth of new blood vessels that cancers need to support their growth, thus preventing the growth of cancer cells.

6. Trabectedin. It is sold as Yondelis, and reduces the cancer-like activities of the cancer cells.